Autologous And Cancer Stem Cell Gene Therapy


Author: Autologous And Cancer, Stem Cell Gene

Date: 01.01.2011

ISBN: 9812775862

Pages: 480

Publisher: World Scientific Publishing Company

Category: Study


Posted on 2012-05-16, by LionFar.

Description

002199a2 medium


Autologous And Cancer Stem Cell Gene Therapy

WORLD SCIENTIFIC PUBLISHING COMPANY |15.09 MB| ISBN-10: 9812775862 | 480 PAGES | PDF | 15.1 MB

Stem cells provide for life-long cell replacement in tissues and organs, and have inherent homing abilities that are critical in therapeutic applications. Stem cells are also the driving force of cancer where genetic/epigenetic alterations culminate in tumorigenesis either in tissue stem cells or in some of their derivatives. As a rare subset of the tumor, cancer stem cells are the only drive of tumor initiation/propagation. Autologous and cancer stem cells are thus the key targets of 1) long-term and transient-regenerative/epigenetic gene therapy and 2) of recurrence-free anticancer therapy, respectively. While cancer stem cell gene therapy still needs time to accomplish, autologous stem cells have been instrumental in the first unequivocal successes for gene therapy whereby ex vivo retrovirally corrected hematopoietic stem cells have been returned to the patients.

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