[share_ebook] Molecular Pathogenesis of Modys: American Diabetes Association Symposium. Scottsdale, Ariz., Usa, November 6-8, 1998 (Frontiers in Diabetes) - Ariz.) American Diabetes Association Symposium (1998 Scottsdale, M. A. Magnuson, F. M. Matschinsky


Author: Ariz.) American Diabetes Association Symposium (1998 Scottsdale, M. A. Magnuson, F. M. Matschinsky

Date: March, 2000

Pages: 271

Publisher: S Karger Pub

Category: Medical

Tag: Medical/Medicine


Posted on 2012-01-09, by 4bookholic.

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Molecular Pathogenesis of Modys: American Diabetes Association Symposium. Scottsdale, Ariz., Usa, November 6-8, 1998 (Frontiers in Diabetes)


Molecular Pathogenesis of Modys: American Diabetes Association Symposium. Scottsdale, Ariz., Usa, November 6-8, 1998 (Frontiers in Diabetes)
Ariz.) American Diabetes Association Symposium (1998 Scottsdale, M. A. Magnuson, F. M. Matschinsky | S Karger Pub | March, 2000 | 271 pages | English | PDF

A timely collection of research papers by 18 leading scientists in the area of biochemical genetics of diabetes mellitus, these contributions focus on a well defined class of monogenic forms of the disease (i.e. MODYs 1-5) all caused by specific mutations or deletion of genes that control pancreatic beta-cell functions: HNF-4alpha, glucokinase, HNF-1alpha, IDX-1 and HNF-1beta. This volume offers a historical perspective of MODYs, and it also contains contributions which deal with the fundamental questions of pancreas and liver development, critical for the understanding of the syndrome complex discussed. Attempts have been made to highlight results and concepts that may be relevant for understanding type-II diabetes in general, exemplified by contributions that connect the field of pancreatic islet cell biology and pathology with the newest findings in the area of insulin action, e.g. the role of the insulin receptor and insulin receptor substrates (IRS 1-3).


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[share_ebook] Molecular Pathogenesis of Modys: American Diabetes Association Symposium. Scottsdale, Ariz., Usa, November 6-8, 1998 (Frontiers in Diabetes) - Ariz.) American Diabetes Association Symposium (1998 Scottsdale, M. A. Magnuson, F. M. Matschinsky

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